Blüm Cannabinoid Ratios Explained

Blüm Ease 1:1:1 THC:CBD:CBG

We selected a balanced 1:1:1 ratio of THC, CBD, and CBG for Blüm Ease to maximise its therapeutic potential for patients experiencing chronic pain, inflammation, and anxiety. Research suggests that this specific combination works synergistically to inhibit pain responses in nerve cells, making it a strong candidate for effective pain relief.¹

CBG, often called the "mother of cannabinoids," interacts with the body's endocannabinoid system differently than THC and CBD. While THC primarily binds to CB1 and CB2 receptors, CBG acts as a partial agonist at both receptors, helping to fine-tune their activity. Additionally, CBG engages with serotonin (5HT1A), a2-adrenoceptors, and other pain and inflammation-related pathways, which may further contribute to its ability to reduce anxiety and stress². Doses of up to 20mg CBG demonstrated a reduction in anxiety for patients without causing cognitive impairment, intoxication, or side effects like heart palpitations or dry mouth³.

By pairing CBG with equal parts THC and CBD, Blüm Ease aims to provide a well-rounded therapeutic effect, leveraging the individual benefits of each cannabinoid while minimizing unwanted side effects. This carefully formulated ratio was designed to provide comprehensive relief, making Blüm   Ease a versatile option for patients seeking a balanced and effective cannabinoid profile.

Blüm Rest 2:1:2 THC:CBD:CBN

Blüm Rest was formulated for patients suffering from insomnia and sleep disturbances, though its benefits may extend beyond these conditions. This formulation of 10 mg THC, 5 mg CBD, and 10 mg CBN, is designed to target CB1 receptors in the central nervous system (CNS), promoting relaxation and preparing the body for sleep while also enhancing sleep quality.

CBN forms through the degradation of THC when cannabis is exposed to heat and oxygen. While cannabis naturally contains only small amounts of CBN, its concentration increases as the plant ages or oxidizes. CBN interacts with the endocannabinoid system (ECS) by weakly binding to CB1 and CB2 receptors, the binding of CB1 receptors is thought to be responsible for contributing to its sleep-enhancing effects⁴. Research also suggests that CBN improves sleep quality by reducing NREM sleep interruptions and nighttime awakenings.

Unlike THC, CBN does not bind as strongly to CB1 receptors and is far less sedative on its own. This is why Blüm Rest includes both THC, CBD, and CBN—THC primarily induces sedation and shortens sleep onset latency, while CBN and CBD enhance overall sleep quality. Together, this balanced formulation supports deeper, more restorative sleep.

Blüm Still 5:1 CBD:CBG

Blüm Still was formulated for chronic pain, anxiety, and patients who may be sensitive to THC or prefer to avoid it. The 25mg CBN and 5mg CBD formulation offers a balanced, effective alternative without affecting cognitive function or daily activities, though its benefits are not limited to these groups.

Research has shown that CBD and CBG together exhibit enhanced anti-inflammatory, antioxidant, and neuroprotective properties compared to either cannabinoid alone⁶. By including both of these non-psychoactive cannabinoids, Blüm Still aims to offer effective relief for inflammatory and chronic pain conditions while also providing relief from anxiety without the cognitive or sedative effects associated with THC.

Blüm Lift 1:5 CBD:THC

Blüm Lift was specifically formulated for patients seeking relief from anxiety, chronic pain, inflammatory conditions, and ADHD⁷. However, like all Blüm formulations, it is not limited to these indications. The 5mg dose of THC, combined with 25mg of CBD, harnesses the synergistic effects of both major psychoactive and non-psychoactive cannabinoids.

CBD has been shown to have anxiolytic (anxiety-reducing), neuroprotective, and calming effects, which can help alleviate chronic pain and inflammatory symptoms. It may also reduce symptoms like hyperactivity and impulsivity in individuals with ADHD. THC, in small doses, provides analgesia and may support mood regulation and focus. However, higher doses of THC can lead to cognitive impairment, including memory deficits and distractibility.

The combination of CBD and THC in specific ratios helps mitigate the cognitive impairment and negative side effects often associated with THC. This allows patients to experience the therapeutic benefits of THC while maintaining mental clarity and functionality. A higher ratio of CBD to THC appears to be more beneficial for balancing therapeutic effects with minimal cognitive impairment^8,9,.